ASCE Plus Derma Signal SRLV ExoSCRT™ Exosome Booster

ASCE Plus SRLV Exosome Exosome Biologic · Rosa damascena exosomes NAD /retinol/peptides Quick Answer ASCE Plus SRLV by ExoCoBio is a Korean dual-vial exosome system built around Rosa damascena (Damask rose) callus extracellular vesicles — plant-derived exosomes with vegan, non-animal origin. The lyophilized powder includes NAD , retinol, ascorbic acid, glutathione, Copper Tripeptide-1, palmitoyl peptides, 19 amino acids, and 4 coenzymes. The 5 mL HA-buffered diluent reconstitutes the powder for topical-via-microchannel or mesotherapy delivery. Last Reviewed May 22, 2026 Manufacturer specification cross-verified Treatment Protocol 1 set per session. 3–4 sessions, 2–4 weeks apart. Maintenance every 2–3 months. Why This Skinbooster Is Different ASCE Plus SRLV uses Rosa damascena callus extracellular vesicles — plant-derived rather than the mammalian stem-cell-derived exosomes typical in the category. This addresses vegan-sourcing concerns and removes the mammalian-origin regulatory ambiguity. The activating diluent doubles as a multi-active concentrate (NAD for cellular energy, retinol for keratinocyte turnover, ascorbic acid for collagen biosynthesis, peptides for signalling). ExoCoBio is the same company behind ASCE exosomes generally and is FDA-listed for the SRLV kit (though not FDA-approved). Mechanism of Action Plant-Derived Exosome (Rosa damascena) Multi-Active Matrix. Fibroblast-derived exosomes (30–150 nm vesicles) carry intercellular signalling cargo — proteins, lipids, miRNA. Once delivered to dermal cells, this cargo communicates regenerative signals: collagen synthesis cues, anti-inflammatory modulation, barrier repair. Application is typically post-procedure to amplify the skin's own repair response. Specifications Product Name ASCE Plus SRLV Exosome Category Exosome Biologic Active Ingredients Vial 1 (powder): Rosa damascena callus extracellular vesicles retinol ascorbic acid glutathione NAD Copper Tripeptide-1 Palmitoyl Pentapeptide-4 acetyl hexapeptide-8 19 amino acids 4 coenzymes trehalose mannitol. Vial 2 (diluent): purified water sodium hyaluronate 19 amino acids sodium phosphate buffer. Mechanism Class Plant-Derived Exosome (Rosa damascena) Multi-Active Matrix Manufacturer ExoCoBio Inc. Origin Republic of Korea Pack 1 × lyophilized exosome powder vial (20 mg) 1 × activating diluent vial (5 mL) Lidocaine Not included Injection Technique Topical post-microneedling or mesotherapy delivery — mix powder diluent immediately before use Injection Depth Topical via microchannels (0.5–1.5 mm) or superficial dermis (1–2 mm) for mesotherapy Recommended Needle 30G–31G for mesotherapy; nano-infusion / microneedling for topical-via-channel delivery Treatment Protocol 1 set per session. 3–4 sessions, 2–4 weeks apart. Maintenance every 2–3 months. Effect Duration 3–6 months cumulative skin quality improvement Storage 2–8 °C refrigerated. Mixed solution use within 24 hours. Shelf Life 24 months unopened (lyophilized) Regulatory Korean MFDS-registered cosmeceutical. FDA-listed (NDC 72951-010) but not FDA-approved as a drug or biologic. Manufactured by ExoCoBio under KGMP and ISO 13485. Plant-derived exosome (vegan, non-animal-origin). SKU FF-SB-ASCE-PLUS-SRLV-EXOSOME Clinical Indications Sensitive, rough, or dry skin Skin barrier compromise Photoaged skin with combined concerns Pigmentation and uneven tone Post-procedure recovery (laser, microneedling, RF) Compare Within Skinbooster Category Unique category on Fillersfairy: ASCE Plus SRLV Exosome is currently the only product in the Exosome Biologic category on this site. Compare with adjacent skinbooster classes via the Related Products section below. �� Read our Complete Exosome Therapy Guide → Frequently Asked Questions What is ASCE Plus SRLV Exosome? ASCE Plus SRLV is a Korean dual-vial exosome system from ExoCoBio. Vial 1 is a lyophilized powder containing Rosa damascena (Damask rose) callus extracellular vesicles plus NAD , retinol, ascorbic acid, glutathione, Copper Tripeptide-1, palmitoyl peptides, 19 amino acids, and 4 coenzymes. Vial 2 is a 5 mL HA-buffered diluent. The two are mixed immediately before use. What does 'SRLV' mean? SRLV refers to the specific exosome composition in this kit — a proprietary ExoCoBio naming convention for the rose-derived vesicle blend. The kit is sometimes labelled 'SRLV-S' (Silver, Korean domestic market) or simply 'SRLV' (Gold, export market). The active formulation is consistent across versions. Why use plant-derived (Rosa damascena) exosomes? Three reasons. (1) Vegan/non-animal origin — addresses ethical and religious concerns about mammalian stem-cell-derived exosomes. (2) Lower regulatory ambiguity in many jurisdictions versus human or animal stem-cell exosomes. (3) Rosa damascena callus extracts have documented anti-inflammatory, antioxidant, and dermal-strengthening effects, providing a botanical regenerative profile. How is ASCE Plus SRLV different from 2XSOME? Both are dual-vial exosome systems. ASCE Plus SRLV uses plant-derived (Rosa damascena callus) exosomes with NAD , retinol, peptides, and amino acids in the powder. 2XSOME (Maypharm) uses stem-cell-derived exosomes with hydrolyzed collagen sodium DNA Cu-tripeptide in the diluent. Different cell sources; ASCE Plus is vegan, 2XSOME is mammalian stem-cell-derived. Is ASCE Plus SRLV FDA approved? It is FDA-listed (NDC 72951-010) as a cosmetic but is not FDA-approved as a drug or biologic. The DailyMed entry includes the disclaimer that the product 'has not been found by FDA to be safe and effective.' Cosmetic registration is distinct from drug or device approval. Verify local jurisdiction regulations before clinical use. How is ASCE Plus SRLV reconstituted? Bring both vials to room temperature. Transfer the full 5 mL diluent into the 20 mg lyophilized powder vial. Gently swirl until fully dissolved — do not shake vigorously, as this can damage exosome integrity. Use the reconstituted solution within 24 hours. Best practice is to mix immediately before the procedure. Why is NAD included? NAD (nicotinamide adenine dinucleotide) is a critical co-factor for cellular energy production, DNA repair (PARP pathway), and sirtuin signalling. Skin NAD declines with age. Adding NAD to the exosome cocktail supports the metabolic substrate that downstream regenerative pathways depend on — an upstream complement to the exosome cargo. How many sessions are typical? 3 to 4 sessions, spaced 2 to 4 weeks apart. Each session uses one full SRLV kit (powder diluent reconstituted). Maintenance is every 2 to 3 months. Post-aggressive-procedure recovery protocols may use weekly sessions during the recovery phase. Can ASCE Plus SRLV be combined with other treatments? Yes — common combinations include post-fractional-laser application, post-RF-microneedling, post-PDRN-injection synergistic protocols, and adjunctive use during downtime recovery. The exosome cargo amplifies the regenerative response triggered by the primary procedure. How much does ASCE Plus SRLV Exosome cost? ASCE Plus SRLV Exosome is priced at USD $103.50 per kit (1 powder vial 1 diluent vial) on Fillersfairy, with wholesale pricing for licensed practitioners. Source verification:→ FDA 510(k) Database (verification) Related Skin Boosters Elaxen PN 2.5ml×3 Polynucleotide (Full Face) 2% PN HA niacinamide Curenex Glow 5×5ml PDRN Skinbooster PDRN 15 peptides glutathione HA Puri Hilo PN 1×2.5ml Polynucleotide HA Hybrid 25 mg PN dual-MW HA (HLD™) Cytocare 516 Skin Booster 10×5ml HA Mesotherapy 16 mg/mL HA CT50® Complex → Browse all Skin Booster products Regulatory Notice. Korean MFDS-registered cosmeceutical. FDA-listed (NDC 72951-010) but not FDA-approved as a drug or biologic. Manufactured by ExoCoBio under KGMP and ISO 13485. Plant-derived exosome (vegan, non-animal-origin). This product is manufactured outside the United States; FDA approval status is product-specific. For licensed healthcare professionals only. Practitioners are responsible for verifying regulatory status of this product in their jurisdiction before clinical use. Not for retail sale. Pricing subject to change.